Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They are really uncommon Within this malignancy when compared to other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and 7% of MBL.seventy five The histone methyltransferase SETD2 and ARID1A are also mutated in a little proportion of individuals. Of